chisturi ovariene~rezistenta la insulina
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0 0intr-unul din mesajele sale la ,,chisturi ovariene" paulaneagu,scria ceva de chestia asta chisturile ovariene paralel de rezistenta org la insulina.Intre timp ce ati aflat?, ca vad ca paula nu ne-a mai scris nimic, referitor la regim si altele -
Depinde si de ce natura sunt chisturile. Am citit si eu despre rezistenta la insulina si se pare ca ar exista o anumita legatura intre 'sindromul ovarului polichistic' si nivelul ridicat de insulina.
Dar atat...nimic despre o legatura cu alte tipuri de chisturi ..ma refer la cele solide..nefunctionale. -
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Diagnosticarea sindromului ovarelor polichistice (PCOS ) este dificila in Ro, nu ca nu ar fi posibil sa se faca analizele dar endocrinologii dela noi sunt mai ciudati.. adica primesti un raspuns de genul... asta e, esti femeie! Oricum este greu de diagnosticat oricum dar in Ro .... mai ales ca medicii romani se agata de ideea.. esti in limitele statistice ( ref analize.. inseamna ca nu-i problema ). In strainataturi este recunoscuta ideea ( la PCOS )ca o analiza incadrabila in valorile normale nu inseamna ca femeia nu are sindromul. Nu toate femeile cu chisturi ovariene au PCOS ..
sau nu toate femeile cu PCOS au si chisturi ovariene.
Printre semnele alarmante ref PCOS sau Sindromul Stein-Leventhal:
- colesterol cu valori foarte mari in conditiile in care persoana nu consuma grasimi decat rar
- hirsutism ( chiar daca testosteronul este inca in limite normale )si un alt ritm de ingrasat / slabit. Vorbesc de variatiile normale din viata fiecareia.
- stari ciudate de depresie, creier de gelatina, foarte lent in reactii ( eu am albit foarte mult ), insomnii , frecvent hipoglicemii / lipotimii chiar la 3-4 ore dupa masa, aritmii si variatii ciudate de Ca / Mg ( chiar daca la analize ies OK ), te ingrasi si cu apa , retentie lichide in tesuturi etc etc
La mine primele analize hormonale au aratat doar ca s-a schimbat raportul LH / FSH. In timp au evoluat, am ajuns la 3 / 1 ( dupa sarcina). Restul hormonilor sunt OK mai putin un exces de 17-OH-progesteron. Din ce mi-au spus unii medici, acest exces este bafta mea - asa a fost posibila sarcina, asa se tin in frau alte simptome. Altii au spus altceva !!!!!
Problemele au avansat de la an la an si sarcina a amplificat totul.
Dar am stat de vorba cu mai multe persoane, de la medici la biochimist, de la roman la american. Incerc sa fac un rezumat:
- se pare ca a doua cauza la amarastenia asta de PCOS este insulina. Nu ca ar iesi clar la analize hiperinsulinemie ci iese aproape de maxim sau foarte putin peste.. cam atat cat sa-ti spuna medicul ca esti inca in limite normale sau sa-ti spuna ca poate fi eroare de laborator. La faze mai avansate iese hiperinsulinemie clara. alta analiza care se mai face in cadrul diagnosticarii PCOS ( in alte tari ) este nivelul de cortizol.. parca!
- prima cauza este alta: perturbarea metabolismului glucozei. Cauze: oboseala, stress ,prea multe glucide si lipsa oxigenarii. Deranjamentul principal este la "sediul central" care intelege ca-s "vremuri grele" si stocheaza rezerve. Se "reseteaza " ceva din valorile normale si organismul nu mai "tolereaza" cantitati normale de glucoza in sange. Pe de alta parte se blocheaza sistemul de tramsformare a grasimilor in glucoza ( adica ceea ce s-a stocat nu se poate folosi ).
- ovarele au receptori sensibili la insulina. Prezenta acesteia in sange duce la hiperstimulare ovariana, secretie mai mare de estrogeni decat poate prelucra organismul chiar daca la analize esti inca in limitele considerate normale. Tot insulina da peste cap si echilibrul colesterolului. Organismul incearca sa depaseasca problemele legate de valurile de estrogeni si-l transforma in testosteron sau depunde pe unde poate ( in grasime se acumuleaza un tip de estrogen si incep sa apara chisturi si alte alea ). Din nou, nivelul acestuia poate sa fie OK la analize ( un timp , evident) dar sa fie peste ceea ce este specific fiecaruia.
Apoi apar si alte probleme. Am inteles ca si barbatii au probleme similare doar ca medicina le priveste di -
fetelor,de ani de zile sindromul asta imi face viata un calvar.Am toate manifestarile descrise,nu ma pot trata fiindca nu tolerez produsele hormonale,m-am ingrasat ,edeme,imi cade parul,obosita ,dar ce ma sperie groaznic e faptul ca pe an ce trece ma fac tot mai lata,in spate,miini,picioare,am crezut ca am adenom hipofizar,am facut 5 tomografii,un RMN,dozari hormonale ptr.hipofiza...si nimic!totul absolut normal dar eu nu mai sunt aceeasi.ajutati-ma cu un sfat sau recomandati-mi, va rog,un endocrinolog bun.va pup!
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Fetelor, si eu am niste probleme care ma duc cu gandul la un posibil PCOS... dar nu sunt sigura, am facut mai demult niste analize si aparent n-aveam nimic (in afara de niste noduli tiroidieni)... In fine, il suspectez si pe medicul de atunci de neseriozitate, deci cred ca ma voi duce, cand voi avea timp, sa-mi fac inca un set de analize.
Dar am tot citit pe net diverse chestii si m-am hotarat sa incerc un tratament naturist - respectiv tratamentul cu extract de palmier pitic (sabal serrulata sau serenoa repens, saw palmetto in engleza), care se foloseste in general impotriva problemelor de prostata. Acest extract inhiba sinteza dehidrotestosteronului, forma activa a testosteronului si echilibreaza astfel nivelul hormonilor din organism.
Va copiez aici un articol despre aceasta planta (in engleza), oricum puteti gasi pe net o gramada de informatii:
Saw Palmetto
Women
Topical saw palmetto has also been used successfully in women for hair loss (androgenic alopecia) due to high levels of male hormone testosterone (4).
Actually the active agent in causing adrogenic hair loss (balding of the head), acne and even excess body hair is a chemical called dihydrotestosterone (DHT). It is formed in the skin by the conversion of testosterone to DHT by an enzyme called 5-alpha reductase. Saw palmetto is known to block 5-alpha reductase as its mechanism to reduce prostatic hypertrophy and androgenic alopecia. To our knowledge it has not been tested as an active agent against acne or excess hair growth (hirsutism) in women either by applying the oil topically (breaking open the capsules) or taking the capsules by mouth. However in theory, by being an effective 5-alpha reductase blocker, it should have a positive effect on both acne and excess hair growth.
Saw Palmetto
Saw palmetto (also know as sabal palmett
is a reddish brown-to-black berry growing on a 6'-8" palm tree (Serenoa repens). The fruit of this palm have been part of the diet of natives of the southeastern U.S. for hundreds of years.
It is widely used for the treatment of enlarged prostate glands in men. It is thought that prostate glands become enlarged primarily because of a metabolite of testosterone, called dihydrotestosterone, or DHT. Women with PCOS (polycystic ovarian syndrome) also tend to have higher levels of testosterone and DHT than other women. Therefore, what works for men may work for women.
Saw Palmetto Extract for Hirsutism
How does it work in women?
One of the most troubling symptoms of women with PCOS is hirsutism (too much hair, in the wrong places). Hirsutism is thought to be mostly due to excessive levels of androgenic hormones. Examples of androgens are testosterone, androstenedione, and DHEA.
Testosterone is the main androgen we’re concerned about. It’s normal for men to have a lot of testosterone and for women to have some. In both men and women, testosterone is converted into a more potent hormone called DHT (dihydrotestosterone). DHT is the hormone in your skin that stimulates hirsutism, which is male pattern hair growth. If you can reduce DHT, you may be able to reduce hirsutism (hair growing where you don't want it) or male pattern hair loss (restoring hair where you do want it).
Saw palmetto appears to reduce DHT in three different ways:
Inhibits DHT production;
Inhibits the binding of DHT to its cell receptors;
Promotes the breakdown of DHT.
Testosterone is converted into DHT by an enzyme called 5-alpha-reductase. 5-alpha-reductase is inhibited by saw palmetto, and thus less DHT is produced and hirsutism may be reduced.
Saw palmetto may be helpful in another way. A high level of estrogen may inhibit the elimination of DHT. Some women with PCOS have estrogen levels that are too high. It is reported to have an anti-estrogenic effect, thus helping with the removal of DHT.
There have been many studies of men with testosterone disorders that demonstrate the effectiveness and safety of saw palmetto. There aren’t yet any studies of hirsute PCOS women. However, naturopathic physicians usin -
using these herbs for PCOS are seeing consistently favorable results.
Saw palmetto may help with the following PCOS symptoms:
Hirsutism (too much hair in the wrong places)
Male pattern baldness or hair loss.
Is It Similar to Anti-Androgenic Drugs?
Two drugs commonly prescribed for PCOS women are spironolactone (Aldactone), and finasteride (Propecia, Proscar).
Spironolactone is a diuretic that blocks two pathways to the production of androgens, or male hormones. One of those pathways is inhibition of 5-alpha-reductase. Spironolactone may cause irregular bleeding in some women, as well as nausea, indigestion or fatigue.
Propecia and Proscar inhibit 5-alpha-reductase and are used mostly for male pattern baldness and men with enlarged prostate glands.
The Journal of the American Medical Association published a review of studies that concluded saw palmetto was as effective as finasteride in the treatment of enlarged prostates.
Two advantages of saw palmetto are:
(1) it is free of side effects, and
(2) it is less expensive than the drugs mentioned above.
Saw Palmetto Side Effects and Precautions
No significant side effects have been noted in clinical trials with this herbal extract, except for rare headache or stomach upset if taken on an empty stomach.
Because of possible hormonal activity, it is not recommended for women who are pregnant or breast-feeding.
Drug Interactions
Palmetto berry constituents have alpha-adrenergic blocking activity that may alter the effects of these medications: prazosin, terazosin, doxazosin mesylate, tamsulosin
It may have an additive effect if taken with anti-androgen drugs that reduce the levels of male sex hormones, such as finasteride (Prosca, Propecia) or flutamide (Eulexin).
In theory, it could interfere with birth control pills or hormone replacement therapy in women.
If you're taking any of these drugs, check with your doctor or naturopathic physician before taking saw palmetto.
Because it may have activity on the body's response to estrogen, the effects of other agents believed to have estrogen-like properties may be altered. Possible examples include alfalfa, black cohosh, bloodroot, burdock, hops, kudzu, licorice, pomegranate, red clover, soy, thyme, white horehound, and yucca.
How Much Should You Take?
Every women is unique, so the amount and form of saw palmetto you need won't be the same as for someone else.
As a general guideline, a common dose for men is 320 mg. of extract per day, standardized to at least 85-95% fatty acids with a guaranteed minimum of 0.2-0.4% sterols. ("Standardized" means you get the same amount of active ingredients every time). You may decide to start with a somewhat lower dose.
In men, it can be taken for six weeks before any effect is noticed. If improvement is noted, it is recommended that men take it continuously. Since you're trying to reduce DHT like the men are, you could do the same.
Vitex and Saw Palmetto Dose
A number of herbal products and nutritional supplements work synergistically to modify your hormonal profile. A few examples include vitex (chasteberry), saw palmetto, and stinging nettles (pygeum). You may wish to combine saw palmetto extract and stinging nettle root for a greater effect. You may also wish to add vitex. As you can imagine, your supplement program can get complicated.
Therefore, we recommend you seek guidance from a naturopathic physician, who would have extensive knowledge of herbs and botanical medicines. Or, consult with Dr. Nancy Dunne, who is a naturopathic physician specializing in the treatment of PCOS.
WARNING: Thee quality of botanical supplements varies widely. Don't buy any herbal or botanical product unless it has a "standardized" amount of the active component listed on the label. A "standardized" product has a consistent amount of active ingredients from one bottle to the next. If you buy a product that is not standardized, you have no clue as to what you are actually getting and may be wasting your money.
You can -
WARNING: Thee quality of botanical supplements varies widely. Don't buy any herbal or botanical product unless it has a "standardized" amount of the active component listed on the label. A "standardized" product has a consistent amount of active ingredients from one bottle to the next. If you buy a product that is not standardized, you have no clue as to what you are actually getting and may be wasting your money.
You can generally obtain the highest quality products from a licensed naturopathic physician. If you wish to order a high-quality saw palmetto or vitex product, call Dr. Nancy Dunne's clinic (Bitterroot Natural Medicine) at 406-728-8544.
Supplemental Nutrient for PCOS
5-hydroxytryptophan
Alpha lipoic acid
Bilberry
Chromium
Cinnamon root
CLA
Fish Oil Yes Yes - Yes - -
Gymnema
Indole 3 carbanol
Licorice
Magnesium
Momordica
NAC
Natural progesterone
Quercetin
Saw Palmetto Yes - Yes - - -
Vanadyl sulfate
Vit. B12 & folic acid
Vitamin B6
Vitex (chasteberry) Yes - - - - -
Zinc -